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Team Captain: Jeavan Lehal
$32223 Raised


Dear friends & family globally!

This May I'm participating in Workout to Conquer Cancer & I want you to join Team Believe!

This is in honour and loving memory of Raj Lehal with all donations going towards Triple negative breast cancer research.

Below are some details of exactly what your donation will be funding:

Increasing Long-Term Survivorship for Triple Negative Breast Cancer

Thanks to discoveries made at BC Cancer, we now know breast cancer is more than 10 different diseases, each with very different prognoses. Triple Negative Breast Cancer (TNBC) can be one of the most deadly, as it is difficult to treat and patients often relapse.

Dr. Aparicios team is now focused on understanding what makes up TNBC and why the immune system does not recognize and eliminate TNBC tumour cells. Using state-of-the-art genomics, including single-cell genomics methods developed here in B.C., scientists have discovered that TNBC has abnormalities in the DNA repair process. When cells divide, these tumours make spelling mistakes which open up potential new treatment options.

Based on this premise, a world-first Phase I trial of a novel drug was recently completed in Canada with promising results. The team is also looking at combination therapies and studying how a persons immune makeup may affect the behaviour of their cancer.

Over the next five years, our BC Cancer team will define single cell genomes from TNBC patient tumours to understand the genomics and tissue immunity of TNBC. They will identify drug targets and initiate clinical studies.

The more knowledge is gained about the biological makeup of TNBC and the role of the immune system, the more new treatments can be designed and combined to eliminate cancer and increase survival. With this knowledge we will be able to improve treatments of early disease to ensure the best chance for long-term survival.

This challenge is more than exercise, it's about joining a community who know that together we can make an impact for those we love and have loved.

So, as I get ready to sweat my way through May, please show your support by making a donation today.

Thank you!